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Correlation between baPWV values and BMP9 levels in hypertensive patients. baPWV, brachial‐ankle pulse wave velocity; BMP9, bone morphogenetic protein 9.

Journal: The Journal of Clinical Hypertension

Article Title: The Association of Circulating Bone Morphogenetic Protein 9 and Arterial Stiffness in Hypertensive Patients

doi: 10.1111/jch.70086

Figure Lengend Snippet: Correlation between baPWV values and BMP9 levels in hypertensive patients. baPWV, brachial‐ankle pulse wave velocity; BMP9, bone morphogenetic protein 9.

Article Snippet: Human BMP9 Duoset ELISA kit (R&D Systems, Catalogue number #DY3209) was used to quantify the plasma BMP9 levels as directed by the instructions.

Techniques:

Odds ratios of circulating BMP9 levels for hypertensive individuals with high (abnormal) baPWV or low (normal) baPWV. Model 1: adjusted for age and gender. Model 2: adjusted for age, gender, and eGFR. Model 3: adjusted for all variables in Model 2 in addition to diabetes and coronary heart disease. Model 4: adjusted for all factors in Model 3 in addition to SBP, DBP, and HR. Model 5: adjusted for all factors in Model 4 in addition to the use of antiplatelet, antilipemic, and antidiabetic agents. DBP, diastolic blood pressure; HR, heart rate; SBP, systolic blood pressure.

Journal: The Journal of Clinical Hypertension

Article Title: The Association of Circulating Bone Morphogenetic Protein 9 and Arterial Stiffness in Hypertensive Patients

doi: 10.1111/jch.70086

Figure Lengend Snippet: Odds ratios of circulating BMP9 levels for hypertensive individuals with high (abnormal) baPWV or low (normal) baPWV. Model 1: adjusted for age and gender. Model 2: adjusted for age, gender, and eGFR. Model 3: adjusted for all variables in Model 2 in addition to diabetes and coronary heart disease. Model 4: adjusted for all factors in Model 3 in addition to SBP, DBP, and HR. Model 5: adjusted for all factors in Model 4 in addition to the use of antiplatelet, antilipemic, and antidiabetic agents. DBP, diastolic blood pressure; HR, heart rate; SBP, systolic blood pressure.

Article Snippet: Human BMP9 Duoset ELISA kit (R&D Systems, Catalogue number #DY3209) was used to quantify the plasma BMP9 levels as directed by the instructions.

Techniques:

ROC curve for BMP9 in predicting arterial stiffness measured by baPWV. AUC, the area under the curve; ROC, receiver operating characteristic.

Journal: The Journal of Clinical Hypertension

Article Title: The Association of Circulating Bone Morphogenetic Protein 9 and Arterial Stiffness in Hypertensive Patients

doi: 10.1111/jch.70086

Figure Lengend Snippet: ROC curve for BMP9 in predicting arterial stiffness measured by baPWV. AUC, the area under the curve; ROC, receiver operating characteristic.

Article Snippet: Human BMP9 Duoset ELISA kit (R&D Systems, Catalogue number #DY3209) was used to quantify the plasma BMP9 levels as directed by the instructions.

Techniques:

Nomogram construction to predict arterial stiffness measured by ages, SBP, diabetes, and BMP9 levels.

Journal: The Journal of Clinical Hypertension

Article Title: The Association of Circulating Bone Morphogenetic Protein 9 and Arterial Stiffness in Hypertensive Patients

doi: 10.1111/jch.70086

Figure Lengend Snippet: Nomogram construction to predict arterial stiffness measured by ages, SBP, diabetes, and BMP9 levels.

Article Snippet: Human BMP9 Duoset ELISA kit (R&D Systems, Catalogue number #DY3209) was used to quantify the plasma BMP9 levels as directed by the instructions.

Techniques:

Incremental effect of BMP9 on predicting arterial stiffness in hypertensive patients. ROC curves of the traditional clinical features and the traditional clinical features plus circulating BMP9 levels for predicting arterial stiffness in hypertensive patients. Clinical features: age ≥ 60 years, diabetes mellitus, SBP ≥ 140 mmHg. ROC, curve receiver operator characteristic curve.

Journal: The Journal of Clinical Hypertension

Article Title: The Association of Circulating Bone Morphogenetic Protein 9 and Arterial Stiffness in Hypertensive Patients

doi: 10.1111/jch.70086

Figure Lengend Snippet: Incremental effect of BMP9 on predicting arterial stiffness in hypertensive patients. ROC curves of the traditional clinical features and the traditional clinical features plus circulating BMP9 levels for predicting arterial stiffness in hypertensive patients. Clinical features: age ≥ 60 years, diabetes mellitus, SBP ≥ 140 mmHg. ROC, curve receiver operator characteristic curve.

Article Snippet: Human BMP9 Duoset ELISA kit (R&D Systems, Catalogue number #DY3209) was used to quantify the plasma BMP9 levels as directed by the instructions.

Techniques:

Reagents and tools table

Journal: EMBO Molecular Medicine

Article Title: BMP-9 mediates fibroproliferation in fibrodysplasia ossificans progressiva through TGF-β signaling

doi: 10.1038/s44321-024-00174-3

Figure Lengend Snippet: Reagents and tools table

Article Snippet: The concentration of BMP-9 in mouse serum was determined using a GDF2/BMP-9 ELISA Kit (LifeSpan BioSciences, LS-F3779) in accordance with the manufacturer’s instructions.

Techniques: Transgenic Assay, Recombinant, Cell Counting, Cell Cycle Assay, Binding Assay, Blocking Assay, Enzyme-linked Immunosorbent Assay, Luciferase, Reporter Assay, Western Blot, Reverse Transcription, Control, Software, Real-time Polymerase Chain Reaction